Ultrasound Can Selectively Kill Cancer Cells
02-05-20
Michael Ortiz, Frank and Ora Lee Marble Professor of Aeronautics and Mechanical Engineering, Emeritus, and Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Bioinspired Engineering; Booth-Kresa Leadership Chair, Center for Autonomous Systems and Technologies; Director, Graduate Aerospace Laboratories; Director, Center for Autonomous Systems and Technologies, are exploring a new technique that could offer a targeted approach to fighting cancer. Low-intensity pulses of ultrasound have been shown to selectively kill cancer cells while leaving normal cells unharmed. In the past, ultrasound waves have been used as a cancer treatment with high-intensity bursts resulting in killing cancer and normal cells. [Caltech story]
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GALCIT
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MCE
Morteza Gharib
Michael Ortiz
Bees "Surf" Atop Water
11-20-19
Chris Roh, Research Engineer, working with Professor Morteza Gharib, discovered a unique way that bees navigate the interface between water and air. When a bee lands on water, the water sticks to its wings, robbing it of the ability to fly. However, that stickiness allows the bee to drag water, creating waves that propel it forward."I was very excited to see this behavior and so I brought the honeybee back to the lab to take a look at it more closely," Roh says. [Caltech release]
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Morteza Gharib
Chris Roh
Professor Gharib Constructs Leonardo da Vinci's Model of Flow
07-16-19
Leonardo da Vinci studied the motion of blood in the human body. He was interested in the heart’s passive, three-cusp aortic valve, which he realized must be operated by the motion of blood. He theorized that vortices curl back to fill the cusps in the flask-shaped constriction at the aorta’s neck. Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Bioinspired Engineering; Booth-Kresa Leadership Chair, Center for Autonomous Systems and Technologies; Director, Graduate Aerospace Laboratories; Director, Center for Autonomous Systems and Technologies, has used modern imaging techniques to demonstrate the existence of the revolving vortices that Leonardo interpreted as closing the valve. [Nature Article]
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Morteza Gharib
"Neural Lander" Uses AI to Land Drones Smoothly
05-23-19
Professors Chung, Anandkumar, and Yue have teamed up to develop a system that uses a deep neural network to help autonomous drones "learn" how to land more safely and quickly, while gobbling up less power. The system they have created, dubbed the "Neural Lander," is a learning-based controller that tracks the position and speed of the drone, and modifies its landing trajectory and rotor speed accordingly to achieve the smoothest possible landing. The new system could prove crucial to projects currently under development at CAST, including an autonomous medical transport that could land in difficult-to-reach locations (such as a gridlocked traffic). "The importance of being able to land swiftly and smoothly when transporting an injured individual cannot be overstated," says Professor Gharib who is the director of CAST; and one of the lead researchers of the air ambulance project. [Caltech story]
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Morteza Gharib
Yisong Yue
Soon-Jo Chung
Animashree Anandkumar
Dragonfly Larvae Inspire New Designs for Prosthetic Heart Valves
07-17-18
Professor Mory Gharib and postdoctoral researcher Chris Roh (MS '13, PhD '17) have studied the design and control of the jets that dragonfly larvae use to propel themselves to re-design health values. "The current heart valve design is a one-size-fits-all, where no patient-specific design is considered, and this causes many post-transplant complications," Dr. Roh says. "We believe that an intentionally off-centered opening of the heart valve to more closely match the patient's original blood flow will be an important design parameter that can be adjusted based on each patient's heart morphology." [Caltech story]
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Morteza Gharib
Chris Roh
postdocs
A Gift of Autonomy
06-21-18
Trustees Lynn Booth and Kent Kresa have decided to endow the Booth-Kresa Leadership Chair for Center for Autonomous Systems and Technologies (CAST). Professor Mory Gharib explains, “in science and technology, freedom is the most powerful gift you can offer. The Booth-Kresa Leadership Chair will help ensure that CAST can move nimbly into our emerging more autonomous future, unleashing the creativity of our faculty, students, and scholars. I am personally grateful to Lynn and Kent for their generosity, enthusiasm, and trust in our vision.” [Breakthrough story]
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Morteza Gharib
Kent Kresa
Lynn Booth
Caltech Trustees
